Published April 25, 2025
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Comparison of structural, optical, and thermal properties in MoS2 based nanocomposites into cancer therapy.

Creators

  • 1. Department of Physics, Shahid Beheshti University, Evin, Tehran, Iran.
  • 2. UNESCO-UNISA Africa Chair in Nanoscience and Nanotechnology College of Graduates Studies, University of South Africa, Muckleneuk Ridge, Pretoria, 392, South Africa. mmahdishahidi@gmail.com.
  • 3. Nanosciences African Network (NANOAFNET)-Materials Research Department, iThemba LABS-National Research Foundation, Somerset West, P.O. Box 722, Cape Town, 7129, South Africa. mmahdishahidi@gmail.com.
  • 4. Department of Basic Sciences, Shahrood Branch, Islamic Azad University, Shahrood, Iran.
  • 5. Islamic Azad University

Description

The objective of the present study is to evaluate the potential of novel molybdenum disulfide (MoS2)-based nanocomposites for photothermal therapy. For this purpose, MoS2-CuS (MoCS) and MoS2-AuNR (MoAu) nanocomposites were synthesized by physically mixing MoS2 suspensions with CuS and AuNRs, respectively. The structural and optical properties of these nanocomposites were characterized using X-ray diffraction (XRD), transmission electron microscopy (TEM), ultraviolet-visible (UV-Vis) spectroscopy, and Fourier transform infrared (FTIR) spectroscopy. The photothermal performance of the nanocomposites was assessed under near-infrared (NIR) radiation at a power density of 1 W/cm2 for 10 min. The results demonstrated that both MoCS and MoAu nanocomposites exhibited enhanced photothermal heating compared to their individual components. Furthermore, the MoAu nanocomposite generated higher photothermal heat than the MoCS nanocomposite. These findings suggest that the MoCS and MoAu nanocomposites have strong potential as novel photothermal agents for cancer therapy.
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