Aqueous extract from leaf of Artocarpus altilis provides cardio-protection from isoproterenol induced myocardial damage in rats: Negative chronotropic and inotropic effects.

Nwokocha, Chukwuemeka R.; Palacios, Javier; Simirgiotis, Mario J.; Thomas, Jemesha; Nwokocha, Magdalene; Young, Lauriann; Thompson, Rory; Cifuentes, Fredi; Paredes, Adrián; Delgoda, Rupika

Published March 22, 2017

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Aqueous extract from leaf of Artocarpus altilis provides cardio-protection from isoproterenol induced myocardial damage in rats: Negative chronotropic and inotropic effects.

1. University of the West Indies
2. Arturo Prat University
3. Austral University of Chile
4. University of Antofagasta

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Publication Details

Journal article

Journal: Journal of ethnopharmacology

Publisher: Elsevier BV

ISSN: 18727573

Volume: 203

Pages: 163-170

Persistent Identifiers

DOI 10.1016/j.jep.2017.03.037 Read more

MAGID 2599231520

PMID 28342858 Read more

Funding

Financial Support

The World Academy of Science/UNESCO — Grant: 13–108 RG/BIO/LA Read more

Fondecyt — Grant: 1140178 Read more

Fondequip — Grant: EQM140002 Read more

Universidad Arturo Prat — Grant: VRIIP0198-14 Read more

References

van Noord . Drug- and non-drug-associated QT interval prolongation, Br. J. Clin.... Read more

Lans . Ethnomedicines used in Trinidad and Tobago for urinary problems and diabe... Read more

Haenen . Reduction of beta-adrenoceptor function by oxidative stress in the hear... Read more

Tappia . Role of oxidative stress in catecholamine-induced changes in cardiac sa... Read more

Yoshikawa . Novel indole S,O-bisdesmoside, calanthoside, the precursor glycoside... Read more

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Showing first 5 of 33 scholarly citations.

MeSH Terms

Animals Artocarpuschemistry Cardiotonic Agentsadministration & dosage Dose-Response Relationship Herb-Drug Interactions Isoproterenoltoxicity Male Myocardial Contractiondrug effects Myocardial Infarctionprevention & control Myocardiumpathology Plant Extractsadministration & dosage Plant Leaves Rats Rats

MeSH (Medical Subject Headings) is the NLM controlled vocabulary for indexing biomedical articles. Click any term to view its definition and hierarchy.

Chemical Substances

Cardiotonic Agents

CAS: 0

D002316

Plant Extracts

CAS: 0

D010936

Isoproterenol

CAS: L628TT009W

D007545

3 chemical substances identified from Medical Subject Headings (MeSH).

Aqueous extract from leaf of Artocarpus altilis provides cardio-protection from isoproterenol induced myocardial damage in rats: Negative chronotropic and inotropic effects.

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Chemical Substances