Published May 20, 2022
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The positive short-term effect of dexamethasone on ataxia symptoms in a patient with ataxia-telangiectasia: A case report.

Creators

  • 1. Vascular and Endovascular Surgery Research Center Mashhad University of Medical Sciences Mashhad Iran.
  • 2. Surgical Oncology Research Center Mashhad University of Medical Sciences Mashhad Iran.
  • 3. International UNESCO center for Health Related Basic Sciences and Human Nutrition Mashhad University of Medical Sciences Mashhad Iran.
  • 4. Department of Pediatric Diseases Faculty of Medicine Mashhad University of Medical Sciences Mashhad Iran.
  • 5. Biotechnology Research Center Pharmaceutical Technology Institute Mashhad University of Medical Sciences Mashhad Iran.
  • 6. Applied Biomedical Research Center Mashhad University of Medical Sciences Mashhad Iran.
  • 7. School of Medicine The University of Western Australia Perth Australia.
  • 8. University of Western Australia
  • 9. Department of Biotechnology School of Pharmacy Mashhad University of Medical Sciences Mashhad Iran.

Description

Oral dexamethasone was administered at a dose of 0.075 mg/kg/day for a boy with ataxia-telangiectasia. The SARA score was improved by 7.0 points after dexamethasone treatment over a period of 28 days. The body weight was increased by 1.4 kg after 4 weeks leading to dose titration to 0.05 mg/kg/day.
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