Published November 19, 2025
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The Association Between Work-Related Stress and Miscarriage in Pregnant Women: A Systematic Review.

  • 1. School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.
  • 2. National and Kapodistrian University of Athens
  • 3. Center for Adolescent Medicine and UNESCO Chair in Adolescent Health Care, First Department of Pediatrics, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece. fbacopoulou@med.uoa.gr.
  • 4. Aghia Sophia Children's Hospital, Athens, Greece. fbacopoulou@med.uoa.gr.
  • 5. Laboratory of Genetics, Department of Biotechnology, School of Applied Biology and Biotechnology, Agricultural University of Athens, Athens, Greece.
  • 6. Department of Primary Care and Population Health, University of Nicosia Medical School, Nicosia, Cyprus.
  • 7. Center for Adolescent Medicine and UNESCO Chair in Adolescent Health Care, First Department of Pediatrics, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.
  • 8. Aghia Sophia Children's Hospital, Athens, Greece.

Description

Miscarriage is a naturally occurring event that can be caused by several factors, such as work-related stress. The aim of the current systematic review was to examine the association between work-related stress and miscarriage in pregnant women, and to corroborate previous findings on the subject. A systematic review was conducted using the PubMed and Scopus databases. Observational studies published in English were considered for inclusion. A total of 412 papers were identified through the database search. After removing duplicates, 302 papers were screened, and based on the inclusion and exclusion criteria, seven studies were included in the systematic review. Our results indicate that there is an increased risk of miscarriage among women with work stress. Future research in larger population samples is needed to confirm these findings.
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